Anesthesia Central is an all-in-one web and mobile solution for treating patients before, during, and after surgery. This collection of drug, procedures and test information is derived from Davis’s Drug, MGH Clinical Anesthesia Procedures, Pocket Guide to Diagnostic Tests, and MEDLINE Journals. Explore these free sample topics:
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The ability of an organ or vascular bed to maintain adequate blood flow despite varying blood pressure is termed autoregulation. Metabolic regulation controls about 75% of all local blood flow in the body. Organs have differing ability (autoregulatory reserve) to increase or decrease their vascular resistance to provide tight coupling between metabolic demand and organ blood flow. Anesthetic agents that cause vasodilation inhibit organ autoregulation. Under these conditions, organ perfusion is more dependent on systemic blood pressure.