Assess eye for signs of infection frequently during week following injection.
Check perfusion of optic nerve head immediately after injection; use tonometry to measure intraocular pressure before and 60 min following the injection.
Adequate analgesia and a broad-spectrum antibiotic should be given prior to injection.
Intravitreal Solution is clear to slightly opalescent and colorless to slightly brownish-yellow. Do not administer solutions that are cloudy, discolored, or contain particulate matter. Store in refrigerator; allow to warm to room temperature for up to 24 hr prior to injection. Do not freeze. Withdraw vial contents through a 5-micron gauge filter needle attached to a 1-mL tuberculin syringe. Discard filter needle after withdrawal. Replace filter needle with sterile 30-gauge x ½-inch needle for intravitreal injection. Expel contents until plunger tip is aligned with line marking 0.05 mL on syringe Each vial should be used for only one eye. If contralateral eye requires treatment, use new vial and equipment.
Explain purpose and side effects of medication to patient. Advise patient to read Patient Information before starting therapy.
Advise patient to notify health care provider of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care provider before taking other medications.
Advise patient to notify ophthalmologist immediately if eye becomes red, sensitive to light, painful, or develops a change in vision.
May cause temporary visual disturbances. Advise patient to avoid driving or other activities requiring good eyesight until response to medication is known.
Rep: May cause fetal harm. Advise women of reproductive potential to notify health care provider if pregnancy is planned or suspected. Advise patient to use highly effective contraception and avoid breastfeeding during and 1 mo after last dose. May impair fertility.