Glycemic Control

First Things First (assess & treat for the following)

• Hyperglycemia occurs in critically ill patients regardless of history of diabetes mellitus.

• Complications of hyperglycemia
  • Volume depletion
  • Impaired erythropoiesis
  • Endothelial dysfunction
  • Increased secretion of pro-inflammatory mediators

• Potential consequences of untreated hyperglycemia
  • Sepsis
  • Decreased kidney function
  • Critical illness polyneuropathy
  • Respiratory failure
  • Increased mortality