Common Street Drugs: Lysergic Acid Diethylamide (LSD)

First Things First (assess & treat for the following)

• LSD is an indole derivative that acts as both serotonin agonist & antagonist, w/ strong hallucinogenic properties.
• Abused for changes in thought, perception, consciousness
• ED visits are usually the result of panic reactions, massive ingestions or accidental ingestions.
• Severe anxiety & agitation may occur.
  • Treat w/ reassurance, minimal stimuli.
  • May respond to benzodiazepines
• Massive ingestions may result in coma, respiratory arrest, HTN, coagulopathy.
  • Maintain airway patency; support w/ oxygenation/ventilation if necessary.
  • Treat hypertensive emergencies w/ sodium nitroprusside.