Clinical Anesthesia Procedures
Anesthesia for Geriatric Patients - Pharmacologic Changes Associated with Aging
Pharmacokinetic Changes in Elderly
Pharmacokinetic Changes in Elderly
- Protein binding of anesthetic drugs is reduced because of decreased levels of circulating serum protein—for example, albumin. Therefore, their pharmacologic effects are potentiated.
- Reduction in blood volume, an increase in percentage of body fat, and decreases in hepatic and renal function result in prolonged elimination for drugs dependent on redistribution and/or elimination for termination of action thereby prolonging anesthetic effects.
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Citation
Pino, Richard M., editor. "Anesthesia for Geriatric Patients - Pharmacologic Changes Associated With Aging." Clinical Anesthesia Procedures, 9th ed., Wolters Kluwer, 2019. Anesthesia Central, anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728319/all/Anesthesia_for_Geriatric_Patients___Pharmacologic_Changes_Associated_with_Aging.
Anesthesia for Geriatric Patients - Pharmacologic Changes Associated with Aging. In: Pino RMR, ed. Clinical Anesthesia Procedures. Wolters Kluwer; 2019. https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728319/all/Anesthesia_for_Geriatric_Patients___Pharmacologic_Changes_Associated_with_Aging. Accessed October 6, 2024.
Anesthesia for Geriatric Patients - Pharmacologic Changes Associated with Aging. (2019). In Pino, R. M. (Ed.), Clinical Anesthesia Procedures (9th ed.). Wolters Kluwer. https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728319/all/Anesthesia_for_Geriatric_Patients___Pharmacologic_Changes_Associated_with_Aging
Anesthesia for Geriatric Patients - Pharmacologic Changes Associated With Aging [Internet]. In: Pino RMR, editors. Clinical Anesthesia Procedures. Wolters Kluwer; 2019. [cited 2024 October 06]. Available from: https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728319/all/Anesthesia_for_Geriatric_Patients___Pharmacologic_Changes_Associated_with_Aging.
* Article titles in AMA citation format should be in sentence-case
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T1 - Anesthesia for Geriatric Patients - Pharmacologic Changes Associated with Aging
ID - 728319
ED - Pino,Richard M,
BT - Clinical Anesthesia Procedures
UR - https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728319/all/Anesthesia_for_Geriatric_Patients___Pharmacologic_Changes_Associated_with_Aging
PB - Wolters Kluwer
ET - 9
DB - Anesthesia Central
DP - Unbound Medicine
ER -
