Medication Errors: Improving Practices and Patient Safety
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It is widely acknowledged that medication errors result in thousands of adverse drug events, preventable reactions, and deaths per year. Nurses, physicians, pharmacists, patient safety organizations, the Food and Drug Administration, the pharmaceutical industry, Health Canada, and other parties share in the responsibility for determining how medication errors occur and designing strategies to reduce error.
One impediment to understanding the scope and nature of the problem has been the reactive "blaming, shaming, training" culture that singled out one individual as the cause of the error. Also historically, medication errors that did not result in patient harm–near-miss situations in which an error could have but didn't happen–or errors that did not result in serious harm were not reported. In contrast, serious errors often instigated a powerful punitive response in which one or a few persons were deemed to be at fault and, as a result, lost their jobs and sometimes their licenses.
In 1999, the Institute of Medicine (IOM) published To Err Is Human: Building a Safer Health System, which drew attention to the problem of medication errors. It pointed out that excellent health care providers do make medication errors, that many of the traditional processes involved in the medication-use system were error-prone, and that other factors, notably drug labeling and packaging, contributed to error. Furthermore, the IOM report, in conjunction with other groups such as the United States Pharmacopeia (USP) and the Institute for Safe Medication Practices (ISMP), called for the redesign of error-prone systems to include processes that anticipated the fallibility of humans working within the system. This initiative is helping shift the way the health care industry addresses medication errors from a single person/bad apple cause to a systems issue.
The National Coordinating Council for Medication Error Reporting and Prevention (NCC-MERP) developed the definition of a medication error that reflects this shift and captures the scope and breadth of the issue:
"A medication error is any preventable event that may cause or lead to inappropriate medication use or patient harm while the medication is in the control of the health care professional, patient, or consumer. Such events may be related to professional practice, health care products, procedures, and systems, including prescribing; order communication; product labeling, packaging, and nomenclature; compounding; dispensing; distribution; administration; education; monitoring; and use."
Inherent in this definition's mention of related factors are the human factors that are part of the medication use system. For example, a nurse or pharmacist may automatically reach into the bin where dobutamine is usually kept, see "do" and "amine" but select dopamine instead of dobutamine. Working amidst distractions, working long hours or shorthanded, and working in a culture where perfection is expected and questioning is discouraged are other examples of the human factors and environmental conditions that contribute to error.
The goal for the design of any individual or hospital-wide medication use system is to determine where systems are likely to fail and to build in safeguards that minimize the potential for error. One way to begin that process is to become familiar with medications or practices that have historically been shown to be involved in serious errors.
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