Specific Considerations with Liver Disease - Hepatic Anatomy

Specific Considerations with Liver Disease - Hepatic Anatomy is a topic covered in the Clinical Anesthesia Procedures.

To view the entire topic, please or purchase a subscription.

Anesthesia Central is an all-in-one web and mobile solution for treating patients before, during, and after surgery. This collection of drug, procedures and test information is derived from Davis’s Drug, MGH Clinical Anesthesia Procedures, Pocket Guide to Diagnostic Tests, and MEDLINE Journals. Explore these free sample topics:

Anesthesia Central

-- The first section of this topic is shown below --

Liver Structure

Liver Structure

  1. The anatomic unit of the liver is lobule. The lobule is composed of hexagonal plates of hepatocytes and portal triads (terminal portal vein, hepatic artery, and bile duct branch) surrounding a central hepatic vein.
  2. Hepatocytes are classified by their position in relation to their portal triad. Those closest to the triad are labeled Zone 1 cells (periportal). These cells receive the most oxygen and nutrients and are responsible for most nitrogen metabolism, oxidation, and gluconeogenesis. Zone 2 is a transitional area. Zone 3 hepatocytes (pericentral) are the farthest from the triad and are at the greatest risk for ischemic injury.

-- To view the remaining sections of this topic, please or purchase a subscription --