Specific Considerations with Endocrine Disease - Adrenal Medullary Disease

Specific Considerations with Endocrine Disease - Adrenal Medullary Disease is a topic covered in the Clinical Anesthesia Procedures.

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Physiology

Preganglionic fibers of the sympathetic nervous system stimulate release of catecholamines from the adrenal medulla. Peripheral effects of catecholamines include chronotropic and inotropic stimulation of the heart, vasomotor changes, enhanced hepatic glycogenolysis, and inhibition of insulin release. Catecholamines are biotransformed in the kidney and liver to metanephrine, normetanephrine, and vanillylmandelic acid.

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Physiology

Preganglionic fibers of the sympathetic nervous system stimulate release of catecholamines from the adrenal medulla. Peripheral effects of catecholamines include chronotropic and inotropic stimulation of the heart, vasomotor changes, enhanced hepatic glycogenolysis, and inhibition of insulin release. Catecholamines are biotransformed in the kidney and liver to metanephrine, normetanephrine, and vanillylmandelic acid.

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