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Neuromuscular Blockade - Reversal of Neuromuscular Blockade

Neuromuscular Blockade - Reversal of Neuromuscular Blockade is a topic covered in the Clinical Anesthesia Procedures.

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Recovery from SCh-induced depolarizing blockade

Recovery from SCh-induced depolarizing blockade usually occurs within 5 to 10 minutes following a 1 mg/kg IV dose. Patients with atypical or inhibited plasma cholinesterase could have a greatly prolonged duration of blockade. Reversal of phase II blockade occurs spontaneously within 10 to 15 minutes in approximately 50% of patients. It is advisable to allow patients with prolonged blockade to recover spontaneously for 20 to 25 minutes and then reversal with an anticholinesterase agent may be attempted if there is no further improvement in twitch strength. Earlier reversal could potentiate the block.

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Citation

Pino, Richard M., editor. "Neuromuscular Blockade - Reversal of Neuromuscular Blockade." Clinical Anesthesia Procedures, 9th ed., Wolters Kluwer, 2019. Anesthesia Central, anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728200/all/Neuromuscular_Blockade___Reversal_of_Neuromuscular_Blockade.
Neuromuscular Blockade - Reversal of Neuromuscular Blockade. In: Pino RM, ed. Clinical Anesthesia Procedures. 9th ed. Wolters Kluwer; 2019. https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728200/all/Neuromuscular_Blockade___Reversal_of_Neuromuscular_Blockade. Accessed March 22, 2019.
Neuromuscular Blockade - Reversal of Neuromuscular Blockade. (2019). In Pino, R. M. (Ed.), Clinical Anesthesia Procedures. Available from https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728200/all/Neuromuscular_Blockade___Reversal_of_Neuromuscular_Blockade
Neuromuscular Blockade - Reversal of Neuromuscular Blockade [Internet]. In: Pino RM, editors. Clinical Anesthesia Procedures. Wolters Kluwer; 2019. [cited 2019 March 22]. Available from: https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728200/all/Neuromuscular_Blockade___Reversal_of_Neuromuscular_Blockade.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Neuromuscular Blockade - Reversal of Neuromuscular Blockade ID - 728200 ED - Pino,Richard M, BT - Clinical Anesthesia Procedures UR - https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728200/all/Neuromuscular_Blockade___Reversal_of_Neuromuscular_Blockade PB - Wolters Kluwer ET - 9 DB - Anesthesia Central DP - Unbound Medicine ER -