Perioperative Hemodynamic Control - β-Adrenergic Antagonists (Table 20.3)

Perioperative Hemodynamic Control - β-Adrenergic Antagonists (Table 20.3) is a topic covered in the Clinical Anesthesia Procedures.

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Propranolol

Propranolol is a nonselective β1- and β2-adrenergic receptor antagonist available in both IV and oral forms. Propranolol is highly lipophilic; it is almost entirely absorbed following oral administration and undergoes up to 75% first-pass clearance by the liver. Hemodynamic effects of propranolol and other β-adrenergic antagonists are secondary to the reduction of cardiac output and suppression of the renin–angiotensin system. β-Adrenergic antagonists can be distinguished by their relative β1 selectivity, their intrinsic sympathomimetic activity, and their pharmacologic half-lives.

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Citation

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TY - ELEC T1 - Perioperative Hemodynamic Control - β-Adrenergic Antagonists (Table 20.3) ID - 728263 Y1 - 2019 PB - Clinical Anesthesia Procedures UR - https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728263/all/Perioperative_Hemodynamic_Control___β_Adrenergic_Antagonists__Table_20_3_ ER -