Transfusion Therapy - Special Considerations
is a topic covered in the Clinical Anesthesia Procedures
To view the entire topic, please sign in or purchase a subscription.
Anesthesia Central is an all-in-one web and mobile solution for treating patients before, during, and after surgery. This collection of drug, procedures and test information is derived from Davis’s Drug, MGH Clinical Anesthesia Procedures, Pocket Guide to Diagnostic Tests, and MEDLINE Journals. Explore these free sample topics:
-- The first section of this topic is shown below --
Hemophilia A and B are rare, sex-linked diseases affecting males almost exclusively. Hemophilia A is due to an abnormality in factor VIII, while hemophilia B (Christmas disease) is due to a factor IX abnormality. The incidence in the United States is 1:10,000 males for hemophilia A and 1:100,000 males for hemophilia.
- Clinical features. Patients usually present early in childhood with hemarthroses and soft tissue hematomas after minor trauma. Laboratory tests demonstrate a markedly prolonged PTT with normal PT and platelet count.
- Treatment with the appropriate factor (of either recombinant or lyophilized concentrate source) should be coordinated with the patient's hematologist. Hemophilia A is treated with factor VIII to achieve preoperative activity levels of 25% to 100%, depending on the extent of the procedure. Some patients with mild hemophilia A may respond to DDAVP therapy. In an emergency, if factor VIII is unavailable, cryoprecipitate transfusion can provide the deficient factor. Hemophilia B is treated with factor IX to achieve at least 30% to 50% activity before surgery.
-- To view the remaining sections of this topic, please sign in or purchase a subscription --
Pino, Richard M., editor. "Transfusion Therapy - Special Considerations." Clinical Anesthesia Procedures, 9th ed., Wolters Kluwer, 2019. Anesthesia Central, anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728386/all/Transfusion_Therapy___Special_Considerations.
Transfusion Therapy - Special Considerations. In: Pino RM, ed. Clinical Anesthesia Procedures. 9th ed. Wolters Kluwer; 2019. https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728386/all/Transfusion_Therapy___Special_Considerations. Accessed April 23, 2019.
Transfusion Therapy - Special Considerations. (2019). In Pino, R. M. (Ed.), Clinical Anesthesia Procedures. Available from https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728386/all/Transfusion_Therapy___Special_Considerations
Transfusion Therapy - Special Considerations [Internet]. In: Pino RM, editors. Clinical Anesthesia Procedures. Wolters Kluwer; 2019. [cited 2019 April 23]. Available from: https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728386/all/Transfusion_Therapy___Special_Considerations.
TY - ELEC
T1 - Transfusion Therapy - Special Considerations
ID - 728386
ED - Pino,Richard M,
BT - Clinical Anesthesia Procedures
UR - https://anesth.unboundmedicine.com/anesthesia/view/ClinicalAnesthesiaProcedures/728386/all/Transfusion_Therapy___Special_Considerations
PB - Wolters Kluwer
ET - 9
DB - Anesthesia Central
DP - Unbound Medicine