Perioperative Hemodynamic Control - Adrenergic Receptor Physiology (Table 20.1)
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Adrenergic receptors can be distinguished by their response to a series of catecholamines. α-Adrenergic receptors are activated by norepinephrine, epinephrine, and isoproterenol in descending order of responsiveness. Beta-adrenergic receptors demonstrate the inverse, with the greatest activity in response to isoproterenol, followed by epinephrine and finally norepinephrine. Receptors that interact exclusively with dopamine are termed dopaminergic. Adrenergic receptors can be further subdivided based on their anatomic location and downstream effects.