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Vancomycin-resistant Enterococcus (VRE)

Vancomycin-resistant Enterococcus (VRE) is a topic covered in the Guide to Diagnostic Tests.

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Organism

Vancomycin-resistant Enterococcus (VRE)

Emergence of VRE seen in both E. faecalis and E. faecium (most common) and at least 7 phenotypes (van A through van G).

VRE, especially E. faecium , usually demonstrates intrinsic resistance to cephalosporins, aminoglycosides, and β-lactam antibiotics.

Enterococci that acquire the van A gene are highly resistant to vancomycin and to teicoplanin. The location of this gene on a plasmid means that it can be spread between strains, and therefore identification of VRE may require contact isolation in the hospital by infection control.

Enterococci can also pass the van A gene cluster to S. aureus resulting in vancomycin-resistant S. aureus .

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Citation

McPhee, Stephen J., et al. "Vancomycin-resistant Enterococcus (VRE)." Guide to Diagnostic Tests, 7th ed., McGraw-Hill Education, 2017. Anesthesia Central, anesth.unboundmedicine.com/anesthesia/view/GDT/619364/all/Vancomycin_resistant_Enterococcus__VRE_.
McPhee SJ, Lu CM, Nicoll D. Vancomycin-resistant Enterococcus (VRE). Guide to Diagnostic Tests. 7th ed. McGraw-Hill Education; 2017. https://anesth.unboundmedicine.com/anesthesia/view/GDT/619364/all/Vancomycin_resistant_Enterococcus__VRE_. Accessed April 25, 2019.
McPhee, S. J., Lu, C. M., & Nicoll, D. (2017). Vancomycin-resistant Enterococcus (VRE). In Guide to Diagnostic Tests. Available from https://anesth.unboundmedicine.com/anesthesia/view/GDT/619364/all/Vancomycin_resistant_Enterococcus__VRE_
McPhee SJ, Lu CM, Nicoll D. Vancomycin-resistant Enterococcus (VRE) [Internet]. In: Guide to Diagnostic Tests. McGraw-Hill Education; 2017. [cited 2019 April 25]. Available from: https://anesth.unboundmedicine.com/anesthesia/view/GDT/619364/all/Vancomycin_resistant_Enterococcus__VRE_.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Vancomycin-resistant Enterococcus (VRE) ID - 619364 A1 - McPhee,Stephen J, AU - Lu,Chuanyi Mark, AU - Nicoll,Diana, BT - Guide to Diagnostic Tests UR - https://anesth.unboundmedicine.com/anesthesia/view/GDT/619364/all/Vancomycin_resistant_Enterococcus__VRE_ PB - McGraw-Hill Education ET - 7 DB - Anesthesia Central DP - Unbound Medicine ER -