AUTOANTIBODIES: FREQUENCY (%) OF AUTOANTIBODIES IN RHEUMATIC DISEASES

AUTOANTIBODIES: FREQUENCY (%) OF AUTOANTIBODIES IN RHEUMATIC DISEASES.1
ANA Anti- dsDNA Rheumatoid Factor Anti-Sm Anti-SS-A Anti-SS-B Anti-SCL-70 Anti-Centromere Anti-Jo-1 ANCA Anti-CCP
Rheumatoid arthritis 30–60 0–5 70 0 0–5 0–2 0 0 0 0 70-80
Systemic lupus erythematosus 95–100 60 20 10–25 15–20 5–20 0 0 0 0–1 30-702
Sjögren syndrome 95 0 75 0 65 65 0 0 0 0 0
Diffuse scleroderma 80–95 0 30 0 0 0 33 1 0 0 0
Limited scleroderma (CREST syndrome) 80–95 0 30 0 0 0 20 50 0 0 0
Polymyositis/dermatomyositis 80–95 0 33 0 0 0 0 0 20–30 0 0
Granulomatosis with polyangiitis 0–15 0 50 0 0 0 0 0 0 93–961 0
1Frequency for generalized, active disease.2 Frequency for SLE with deforming erosive arthritis.
Anti-dsDNA = anti-double-stranded DNA antibody; ANA = antinuclear antibodies; ANCA = antineutrophil cytoplasmic antibody; Anti-CCP = antibodies to cyclic citrullinated peptide; Anti-Jo-1 = antibodies directed against histidyl-tRNA synthetase; Anti-Sm = anti-Smith antibody; Anti-SCL-70 = anti-scleroderma antibody; Anti-SSA = antibodies to Ro (SSA) cellular ribonucleoprotein complexes of two types (52 kDa and 60 kDa); Anti-SSB = antibodies to La (SSB) cellular ribonucleoprotein complexes; CREST = C alcinosis cutis, R aynaud phenomenon, E sophageal motility disorder, S clerodactyly, and T elangiectasia.
Reproduced with permission from Papadakis MA, McPhee SJ, Rabow MW (editors). Current Medical Diagnosis & Treatment 2016, 55th ed., McGraw-Hill, 2016.
AUTOANTIBODIES: FREQUENCY (%) OF AUTOANTIBODIES IN RHEUMATIC DISEASES is a sample topic from the Guide to Diagnostic Tests.

To view other topics, please or .

Anesthesia Central is an all-in-one web and mobile solution for treating patients before, during, and after surgery. This collection of drugs, procedures, and test information is derived from Davis’s Drug, MGH Clinical Anesthesia Procedures, Pocket Guide to Diagnostic Tests, and PRIME Journals. .