Ethylene Glycol, Methanol, Propylene Glycol, and Isopropyl Alcohol Ingestion
First Things First (assess & treat for the following)
- Diagnosis & early treatment require a high index of suspicion with the proper setting even w/o supporting lab data.
- Obtundation & increased anion or osmolal gap: think of the toxic alcohol ingestions.
- Highest priority is maintenance of the ABCs.
- Then detoxification/elimination:
- Charcoal is not helpful.
- Lavage only if within 1 hour of recent large-volume ingestion
- Then correct metabolic abnormalities
- Goal is to prevent development of toxic metabolites
- OG = (2 x Na) + BUN/2.8 + Glucose/18 + EtOH/4.6
- Normal OG is 12 +/- 2
- AG = Na - Cl + HCO3
- Normal AG is 12 +/- 4
- Normal AG is 12 +/- 4
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Last updated: April 16, 2010
Citation
"Ethylene Glycol, Methanol, Propylene Glycol, and Isopropyl Alcohol Ingestion." Pocket ICU Management, PocketMedicine.com, Inc, 2010. Anesthesia Central, anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534035/all/Ethylene_Glycol__Methanol__Propylene_Glycol__and_Isopropyl_Alcohol_Ingestion.
Ethylene Glycol, Methanol, Propylene Glycol, and Isopropyl Alcohol Ingestion. Pocket ICU Management. PocketMedicine.com, Inc; 2010. https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534035/all/Ethylene_Glycol__Methanol__Propylene_Glycol__and_Isopropyl_Alcohol_Ingestion. Accessed October 7, 2024.
Ethylene Glycol, Methanol, Propylene Glycol, and Isopropyl Alcohol Ingestion. (2010). In Pocket ICU Management. PocketMedicine.com, Inc. https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534035/all/Ethylene_Glycol__Methanol__Propylene_Glycol__and_Isopropyl_Alcohol_Ingestion
Ethylene Glycol, Methanol, Propylene Glycol, and Isopropyl Alcohol Ingestion [Internet]. In: Pocket ICU Management. PocketMedicine.com, Inc; 2010. [cited 2024 October 07]. Available from: https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534035/all/Ethylene_Glycol__Methanol__Propylene_Glycol__and_Isopropyl_Alcohol_Ingestion.
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T1 - Ethylene Glycol, Methanol, Propylene Glycol, and Isopropyl Alcohol Ingestion
ID - 534035
Y1 - 2010/04/16/
BT - Pocket ICU Management
UR - https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534035/all/Ethylene_Glycol__Methanol__Propylene_Glycol__and_Isopropyl_Alcohol_Ingestion
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