First Things First
- Cyanosis in the face of normal PaO2 is key item.
- Tissue dysoxia and hypoxia cause the deleterious signs/symptoms seen.
- This state causes significant tissue hypoxia, cyanosis and oxidative stress.
- This stressful oxidative state can also lead to hemolysis.
- Supportive treatment
- High-concentration FiO2 to saturate remaining normal HgG
- In symptomatic pts, consider methylene blue (see below).
- Most patients respond within 15-30 minutes.
- Poison control is a good resource for management.
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Last updated: May 9, 2010
"Methemoglobinemia." Pocket ICU Management, PocketMedicine.com, Inc, 2010. Anesthesia Central, anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534069/all/Methemoglobinemia.
Methemoglobinemia. Pocket ICU Management. PocketMedicine.com, Inc; 2010. https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534069/all/Methemoglobinemia. Accessed May 30, 2023.
Methemoglobinemia. (2010). In Pocket ICU Management. PocketMedicine.com, Inc. https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534069/all/Methemoglobinemia
Methemoglobinemia [Internet]. In: Pocket ICU Management. PocketMedicine.com, Inc; 2010. [cited 2023 May 30]. Available from: https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534069/all/Methemoglobinemia.
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TY - ELEC T1 - Methemoglobinemia ID - 534069 Y1 - 2010/05/09/ BT - Pocket ICU Management UR - https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534069/all/Methemoglobinemia PB - PocketMedicine.com, Inc DB - Anesthesia Central DP - Unbound Medicine ER -