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Catheter-Related Bloodstream Infection (CRBSI)

Catheter-Related Bloodstream Infection (CRBSI) is a topic covered in the Pocket ICU Management.

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First Things First (assess and treat for the following)

  • These infections are primarily due to central venous catheters (CVCs) but could also involve peripherally inserted venous or arterial access, or even drains (including urinary catheters). Can consider short- or long-term CVC.
  • Risk of infection is related primarily to insertion factors and duration of use. Other factors include host defenses, multiple organ failure, or ongoing sepsis.
  • CRBSIs significantly increase hospital morbidity and mortality. The diagnosis can be based on microbiological confirmation from the catheter or sepsis with clinical concern for the catheter as the source. A higher degree of suspicion is required for cultures of organisms usually classified as skin contaminants.
  • CRBSIs can be either primary or secondary (originating from a focus of infection elsewhere).
  • Management of CRBSI usually involves removal of the infected catheter (as well as other simultaneous catheters if possible), antibiotic therapy, and appropriate antibiotic coverage.
  • Hemodynamic management is as for other causes of sepsis.

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Last updated: May 12, 2010


"Catheter-Related Bloodstream Infection (CRBSI)." Pocket ICU Management, PocketMedicine.com, Inc, 2010. Anesthesia Central, anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534076/all/Catheter_Related_Bloodstream_Infection__CRBSI_.
Catheter-Related Bloodstream Infection (CRBSI). Pocket ICU Management. PocketMedicine.com, Inc; 2010. https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534076/all/Catheter_Related_Bloodstream_Infection__CRBSI_. Accessed April 20, 2019.
Catheter-Related Bloodstream Infection (CRBSI). (2010). In Pocket ICU Management. Available from https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534076/all/Catheter_Related_Bloodstream_Infection__CRBSI_
Catheter-Related Bloodstream Infection (CRBSI) [Internet]. In: Pocket ICU Management. PocketMedicine.com, Inc; 2010. [cited 2019 April 20]. Available from: https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534076/all/Catheter_Related_Bloodstream_Infection__CRBSI_.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Catheter-Related Bloodstream Infection (CRBSI) ID - 534076 Y1 - 2010/05/12/ BT - Pocket ICU Management UR - https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534076/all/Catheter_Related_Bloodstream_Infection__CRBSI_ PB - PocketMedicine.com, Inc DB - Anesthesia Central DP - Unbound Medicine ER -