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Common Street Drugs: Phencyclidine (PCP)

Common Street Drugs: Phencyclidine (PCP) is a topic covered in the Pocket ICU Management.

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Anesthesia Central

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First Things First (assess & treat for the following)

  • Phencyclidine is a potent analgesic & dissociative anesthetic w/ hallucinogenic properties.
  • Usual 5-mg doses result in lethargy, euphoria, hallucinations.
  • Large doses can result in increased autonomic effects, including HTN, hyperthermia, tachycardia, seizures.
    • HTN is common. Most cases resolve in 4 hrs but may last >24 hrs. Treat symptomatic hypertensive crisis w/ IV nitroprusside.
    • Treat seizure activity w/ a benzodiazepine.
  • Violent behavior & combativeness are common; control w/ haloperidol or a benzodiazepine.
  • Enterohepatic/gastroenteric cycles & storage in lipids account for prolonged symptoms.

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Last updated: April 15, 2010


"Common Street Drugs: Phencyclidine (PCP)." Pocket ICU Management, PocketMedicine.com, Inc, 2010. Anesthesia Central, anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534205/all/Common_Street_Drugs:_Phencyclidine__PCP_.
Common Street Drugs: Phencyclidine (PCP). Pocket ICU Management. PocketMedicine.com, Inc; 2010. https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534205/all/Common_Street_Drugs:_Phencyclidine__PCP_. Accessed April 23, 2019.
Common Street Drugs: Phencyclidine (PCP). (2010). In Pocket ICU Management. Available from https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534205/all/Common_Street_Drugs:_Phencyclidine__PCP_
Common Street Drugs: Phencyclidine (PCP) [Internet]. In: Pocket ICU Management. PocketMedicine.com, Inc; 2010. [cited 2019 April 23]. Available from: https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534205/all/Common_Street_Drugs:_Phencyclidine__PCP_.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Common Street Drugs: Phencyclidine (PCP) ID - 534205 Y1 - 2010/04/15/ BT - Pocket ICU Management UR - https://anesth.unboundmedicine.com/anesthesia/view/Pocket-ICU-Management/534205/all/Common_Street_Drugs:_Phencyclidine__PCP_ PB - PocketMedicine.com, Inc DB - Anesthesia Central DP - Unbound Medicine ER -